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There has been concern expressed both by patients and caregivers related to asthma management and the implications of providing oral steroids during an asthma exacerbation during this pandemic. “oral corticosteroids for the control of asthma symptoms and exacerbations have been a mainstay of treatment for over four decades, but carry serious health risks if overused,” said eugene bleecker, md, co-chief, division of genetics, genomics and precision medicine, department of medicine, university of arizona health sciences. The steroids used to treat asthma are known as corticosteroids. Corticosteroids are copies of hormones your body produces naturally. Steroids help asthma by calming inflamed airways and stopping inflammation. This helps ease asthma symptoms such as breathlessness and coughing. While this study was only a single-blind one, the authors have providedsome insight into the duration of steroids for copd exacerbations. Anevidence-based approach to treating copd exacerbations would suggestthat the appropriate duration of therapy is in the range of 5 days to 2weeks. The 10-day course has been studied best. The pathophysiologic basis for the use of corticosteroids in copd/asthma exacerbations resides in their ability to reduce airway inflammation. Patients having an asthma exacerbation are instructed to self-administer 2 to 4 puffs of inhaled albuterol or a similar short-acting beta-2 agonist up to 3 times spaced 20 minutes apart for an acute exacerbation and to measure peak expiratory flow (pef) if possible. Maintaining good asthma control helps minimize risk of an asthma exacerbation. There is no good evidence that inhaled glucocorticoids or the biologic agents used for asthma have an adverse effect on the course of covid-19 infection [ 5,10 ]. Viruses are common triggers of asthma exacerbations and the current sars-cov-2 pandemic raises several questions regarding the optimum management strategies. Here, we discuss the contentious issue of whether the mainstay therapy systemic corticosteroids should be used in the routine management of covid-19-associated asthma exacerbations. Background: several studies showed that inhaled corticosteroids (ics) may be a potential treatment in acute asthma exacerbation in children. This study was an update meta-analysis on the roles of ics in the management of acute asthma exacerbation in children presenting to the hospital. -exogenous corticosteroids suppress adrenocorticoid activity the least when given at the time of maximal activity; consider time of maximal adrenal cortex activity (2 to 8 am) when dosing. Short courses of systemic corticosteroids (scs), both oral and injectable, are very effective for the resolution of acute asthma symptoms, including exacerbations. However, the benefits of scs, even short courses, must be balanced against the impact of their side-effects https://vk.com/topic-174425918_47780100

 

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